María Eugenia López
Investigador sénior
Envejecimiento sano y patológico
Email:
mariaelo@ucm.es
Phone number: (+34) 91 3364656 ext. 79317
ORCID: 0000-0002-3928-2629
Google scholar: https://scholar.google.es/citations?user=scqB4QkAAAAJ
ResearchGate: https://www.researchgate.net/profile/Maria_Lopez283
Comencé mi trayectoria investigadora en el Laboratorio de Neurociencia Cognitiva y Computacional en el año 2009, y actualmente soy Profesora Contratada Doctora en el Dep. Psicología Experimental de la Universidad Complutense de Madrid. Mi principal línea de investigación se centra en el estudio del Envejecimiento sano y patológico, aunque también colaboro en otras líneas, como en Neurociencia clínica.
Principales publicaciones
2021
- Sanchez-Bornot JM, Lopez ME, Bruña R, Maestu F, Youssofzadeh V, Yang S, Finn DP, Todd S, McLean PL, Prasad G, Wong-Lin K. High-dimensional brain-wide functional connectivity mapping in magnetoencephalography. J Neurosci Methods. 2021 01; 348:108991. PubMed ID: 33181166.
2020
- López ME, Turrero A, Cuesta P, Rodríguez-Rojo IC, Barabash A, Marcos A, Maestú F, Fernández A. A multivariate model of time to conversion from mild cognitive impairment to Alzheimer's disease. Geroscience. 2020 12; 42(6):1715-1732. PubMed ID: 32886293.
2019
- Novellino F, López ME, Vaccaro MG, Miguel Y, Delgado ML, Maestu F. Association Between Hippocampus, Thalamus, and Caudate in Mild Cognitive Impairment APOEε4 Carriers: A Structural Covariance MRI Study. Front Neurol. 2019; 10:1303. PubMed ID: 31920926. PDF file.
- Pusil S, López ME, Cuesta P, Bruña R, Pereda E, Maestú F. Hypersynchronization in mild cognitive impairment: the 'X' model. Brain. 2019 12; 142(12):3936-3950. PubMed ID: 31633176. PDF file.
- Pusil S, Dimitriadis SI, López ME, Pereda E, Maestú F. Aberrant MEG multi-frequency phase temporal synchronization predicts conversion from mild cognitive impairment-to-Alzheimer's disease. Neuroimage Clin. 2019; 24:101972. PubMed ID: 31522127. PDF file.
- Dimitriadis SI, López ME, Maestu F, Pereda E. Modeling the Switching Behavior of Functional Connectivity Microstates (FCμstates) as a Novel Biomarker for Mild Cognitive Impairment. Front Neurosci. 2019; 13:542. PubMed ID: 31244592. PDF file.
- Platero C, López ME, Carmen Tobar MD, Yus M, Maestu F. Discriminating Alzheimer's disease progression using a new hippocampal marker from T1-weighted MRI: The local surface roughness. Hum Brain Mapp. 2019 04; 40(5):1666-1676. PubMed ID: 30451343. PDF file.
- López ME, Pusil S, Pereda E, Maestú F, Barceló F. Dynamic low frequency EEG phase synchronization patterns during proactive control of task switching. Neuroimage. 2019 02; 186:70-82. PubMed ID: 30394328. PDF file.
2018
- Susi G, Antón Toro L, Canuet L, López ME, Maestú F, Mirasso CR, Pereda E. A Neuro-Inspired System for Online Learning and Recognition of Parallel Spike Trains, Based on Spike Latency, and Heterosynaptic STDP. Front Neurosci. 2018; 12:780. PubMed ID: 30429767. PDF file.
- Rodríguez-Rojo IC, Cuesta P, López ME, de Frutos-Lucas J, Bruña R, Pereda E, Barabash A, Montejo P, Montenegro-Peña M, Marcos A, López-Higes R, Fernández A, Maestú F. Val66Met Polymorphism and Gamma Band Disruption in Resting State Brain Functional Connectivity: A Magnetoencephalography Study in Cognitively Intact Older Females. Front Neurosci. 2018; 12:684. PubMed ID: 30333719. PDF file.
- de Frutos-Lucas J, López-Sanz D, Zuluaga P, Rodríguez-Rojo IC, Luna R, López ME, Delgado-Losada ML, Marcos A, Barabash A, López-Higes R, Maestú F, Fernández A. Physical activity effects on the individual alpha peak frequency of older adults with and without genetic risk factors for Alzheimer's Disease: A MEG study. Clin Neurophysiol. 2018 09; 129(9):1981-1989. PubMed ID: 30031969. PDF file.
- Martínez JH, López ME, Ariza P, Chavez M, Pineda-Pardo JA, López-Sanz D, Gil P, Maestú F, Buldú JM. Functional brain networks reveal the existence of cognitive reserve and the interplay between network topology and dynamics. Sci Rep. 2018 Jul; 8(1):10525. PubMed ID: 30002460. PDF file.
- Dimitriadis SI, López ME, Bruña R, Cuesta P, Marcos A, Maestú F, Pereda E. How to Build a Functional Connectomic Biomarker for Mild Cognitive Impairment From Source Reconstructed MEG Resting-State Activity: The Combination of ROI Representation and Connectivity Estimator Matters. Front Neurosci. 2018; 12:306. PubMed ID: 29910704. PDF file.
2017
- López ME, Turrero A, Delgado ML, Rodríguez-Rojo IC, Arrazola J, Barabash A, Maestú F, Fernández A. APOE ε4 Genotype and Cognitive Reserve Effects on the Cognitive Functioning of Healthy Elders. Dement Geriatr Cogn Disord. 2017; 44(5-6):328-342. PubMed ID: 29414814. PDF file.
- López ME, Engels MMA, van Straaten ECW, Bajo R, Delgado ML, Scheltens P, Hillebrand A, Stam CJ, Maestú F. MEG Beamformer-Based Reconstructions of Functional Networks in Mild Cognitive Impairment. Front Aging Neurosci. 2017; 9:107. PubMed ID: 28487647. PDF file.
2016
- Aurtenetxe S, García-Pacios J, Del Río D, López ME, Pineda-Pardo JA, Marcos A, Delgado Losada ML, López-Frutos JM, Maestú F. Interference Impacts Working Memory in Mild Cognitive Impairment. Front Neurosci. 2016; 10:443. PubMed ID: 27790082. PDF file.
- López ME, Turrero A, Cuesta P, López-Sanz D, Bruña R, Marcos A, Gil P, Yus M, Barabash A, Cabranes JA, Maestú F, Fernández A. Searching for Primary Predictors of Conversion from Mild Cognitive Impairment to Alzheimer's Disease: A Multivariate Follow-Up Study. J Alzheimers Dis. 2016 03; 52(1):133-43. PubMed ID: 27060953. PDF file.
2015
- Maestú F, Peña JM, Garcés P, González S, Bajo R, Bagic A, Cuesta P, Funke M, Mäkelä JP, Menasalvas E, Nakamura A, Parkkonen L, López ME, Del Pozo F, Sudre G, Zamrini E, Pekkonen E, Henson RN, Becker JT, . A multicenter study of the early detection of synaptic dysfunction in Mild Cognitive Impairment using Magnetoencephalography-derived functional connectivity. Neuroimage Clin. 2015; 9:103-9. PubMed ID: 26448910. PDF file.
- Canuet L, Pusil S, López ME, Bajo R, Pineda-Pardo JÁ, Cuesta P, Gálvez G, Gaztelu JM, Lourido D, García-Ribas G, Maestú F. Network Disruption and Cerebrospinal Fluid Amyloid-Beta and Phospho-Tau Levels in Mild Cognitive Impairment. J Neurosci. 2015 Jul; 35(28):10325-30. PubMed ID: 26180207. PDF file.
- Bajo R, Pusil S, López ME, Canuet L, Pereda E, Osipova D, Maestú F, Pekkonen E. Scopolamine effects on functional brain connectivity: a pharmacological model of Alzheimer's disease. Sci Rep. 2015 Jul; 5:9748. PubMed ID: 26130273. PDF file.
- Cuesta P, Garcés P, Castellanos NP, López ME, Aurtenetxe S, Bajo R, Pineda-Pardo JA, Bruña R, Marín AG, Delgado M, Barabash A, Ancín I, Cabranes JA, Fernandez A, Del Pozo F, Sancho M, Marcos A, Nakamura A, Maestú F. Influence of the APOE ε4 allele and mild cognitive impairment diagnosis in the disruption of the MEG resting state functional connectivity in sources space. J Alzheimers Dis. 2015; 44(2):493-505. PubMed ID: 25281603. PDF file.
- Cuesta P, Barabash A, Aurtenetxe S, Garcés P, López ME, Bajo R, Llanero-Luque M, Ancín I, Cabranes JA, Marcos A, Sancho M, Nakamura A, Maestú F, Fernandez A. Source analysis of spontaneous magnetoencephalograpic activity in healthy aging and mild cognitive impairment: influence of apolipoprotein E polymorphism. J Alzheimers Dis. 2015; 43(1):259-73. PubMed ID: 25079806. PDF file.
2014
- Garcés P, Angel Pineda-Pardo J, Canuet L, Aurtenetxe S, López ME, Marcos A, Yus M, Llanero-Luque M, Del-Pozo F, Sancho M, Maestú F. The Default Mode Network is functionally and structurally disrupted in amnestic mild cognitive impairment - a bimodal MEG-DTI study. Neuroimage Clin. 2014; 6:214-21. PubMed ID: 25379433. PDF file.
- López ME, Bruña R, Aurtenetxe S, Pineda-Pardo JÁ, Marcos A, Arrazola J, Reinoso AI, Montejo P, Bajo R, Maestú F. Alpha-band hypersynchronization in progressive mild cognitive impairment: a magnetoencephalography study. J Neurosci. 2014 Oct; 34(44):14551-9. PubMed ID: 25355209. PDF file.
- López ME, Aurtenetxe S, Pereda E, Cuesta P, Castellanos NP, Bruña R, Niso G, Maestú F, Bajo R. Cognitive reserve is associated with the functional organization of the brain in healthy aging: a MEG study. Front Aging Neurosci. 2014; 6:125. PubMed ID: 24982632. PDF file.
- López ME, Garcés P, Cuesta P, Castellanos NP, Aurtenetxe S, Bajo R, Marcos A, Montenegro M, Yubero R, del Pozo F, Sancho M, Maestú F. Synchronization during an internally directed cognitive state in healthy aging and mild cognitive impairment: a MEG study. Age (Dordr). 2014 Jun; 36(3):9643. PubMed ID: 24658709. PDF file.
- Pineda-Pardo JA, Garcés P, López ME, Aurtenetxe S, Cuesta P, Marcos A, Montejo P, Yus M, Hernández-Tamames JA, del Pozo F, Becker JT, Maestú F. White matter damage disorganizes brain functional networks in amnestic mild cognitive impairment. Brain Connect. 2014 Jun; 4(5):312-22. PubMed ID: 24617580. PDF file.
- López ME, Cuesta P, Garcés P, Castellanos PN, Aurtenetxe S, Bajo R, Marcos A, Delgado ML, Montejo P, López-Pantoja JL, Maestú F, Fernandez A. MEG spectral analysis in subtypes of mild cognitive impairment. Age (Dordr). 2014 Jun; 36(3):9624. PubMed ID: 24532390. PDF file.
- Coullaut-Valera R, Arbaiza I, Bajo R, Arrúe R, López ME, Coullaut-Valera J, Correas A, López-Sanz D, Maestu F, Papo D. Drug polyconsumption is associated with increased synchronization of brain electrical-activity at rest and in a counting task. Int J Neural Syst. 2014 Feb; 24(1):1450005. PubMed ID: 24344693. PDF file.
- Gonzalez-Moreno A, Aurtenetxe S, Lopez-Garcia ME, del Pozo F, Maestu F, Nevado A. Signal-to-noise ratio of the MEG signal after preprocessing. J Neurosci Methods. 2014 Jan; 222:56-61. PubMed ID: 24200506. PDF file.
2013
- Garcés P, Vicente R, Wibral M, Pineda-Pardo JÁ, López ME, Aurtenetxe S, Marcos A, de Andrés ME, Yus M, Sancho M, Maestú F, Fernández A. Brain-wide slowing of spontaneous alpha rhythms in mild cognitive impairment. Front Aging Neurosci. 2013; 5:100. PubMed ID: 24409145. PDF file.
2012
- Bajo R, Castellanos NP, López ME, Ruiz JM, Montejo P, Montenegro M, Llanero M, Gil P, Yubero R, Baykova E, Paul N, Aurtenetxe S, Del Pozo F, Maestu F. Early dysfunction of functional connectivity in healthy elderly with subjective memory complaints. Age (Dordr). 2012 Apr; 34(2):497-506. PubMed ID: 21468670. PDF file.
Otras publicaciones
Jaisalmer de Frutos-Lucas, David López-Sanz, Pablo Cuesta, Ricardo Bruña, Sofía de la Fuente, Noelia Serrano, María Eugenia López, María Luisa Delgado-Losada, Ramón López-Higes, Alberto Marcos, and Fernando Maestú. Enhancement of posterior brain functional networks in bilingual older adults. Bilingualism: Language and Cognition. 2019; https://doi.org/10.1017/S1366728919000178
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