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David López-Sanz

Research staff
Healthy and pathological aging

Email: david.lopez@ctb.upm.es
Phone number: (+34) 91 3364642
ORCID: 0000-0001-5294-4407
Google scholar: https://scholar.google.es/citations?hl=es&user=xUjM1kEAAAAJ

I joined the Laboratory of Cognitive and Computational Neuroscience in 2010 after finishing my Degree in Psychology and my MsC in Neuroscience. I have worked in the field of the early detection of Alzheimer´s Disease, more concretely in the characterization of Subjective Cognitive Decline (SCD). Afterwards I obtained a post-doc grant from the Juan de la Cierva program (Spanish Ministry of Science) in the UAM during 2020. I am currently an Assistant Lecturer at the UCM in the Department of Psychobiology.

Other research interests

Clinical neuroscience

This research line is focused on the clinical appliance of electrophysiological biomarkers. These biomarkers are developed by studying, with MEG and EEG, the electromagnetic brain activity of patients with neurological disorders. This line participates in the studies that involve patients with epilepsy, stroke, dementia, autism, or ADHD.

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Main publications

2020

  • de Frutos-Lucas J, Cuesta P, López-Sanz D, Peral-Suárez Á, Cuadrado-Soto E, Ramírez-Toraño F, Brown BM, Serrano JM, Laws SM, Rodríguez-Rojo IC, Verdejo-Román J, Bruña R, Delgado-Losada ML, Barabash A, López-Sobaler AM, López-Higes R, Marcos A, Maestú F. The relationship between physical activity, apolipoprotein E ε4 carriage, and brain health. Alzheimers Res Ther. 2020 04; 12(1):48. PubMed ID: 32331531.
  • Filippi R, Periche Tomas E, Papageorgiou A, Bright P. A role for the cerebellum in the control of verbal interference: Comparison of bilingual and monolingual adults. PLoS One. 2020; 15(4):e0231288. PubMed ID: 32315339.
  • Shumbayawonda E, López-Sanz D, Bruña R, Serrano N, Fernández A, Maestú F, Abasolo D. Complexity changes in preclinical Alzheimer's disease: An MEG study of subjective cognitive decline and mild cognitive impairment. Clin Neurophysiol. 2020 02; 131(2):437-445. PubMed ID: 31884374.
  • Serrano N, López-Sanz D, Bruña R, Garcés P, Rodríguez-Rojo IC, Marcos A, Crespo DP, Maestú F. Spatiotemporal Oscillatory Patterns During Working Memory Maintenance in Mild Cognitive Impairment and Subjective Cognitive Decline. Int J Neural Syst. 2020 Jan; 30(1):1950019. PubMed ID: 31522594.

2019

  • Hughes LE, Henson RN, Pereda E, Bruña R, López-Sanz D, Quinn AJ, Woolrich MW, Nobre AC, Rowe JB, Maestú F, . Biomagnetic biomarkers for dementia: A pilot multicentre study with a recommended methodological framework for magnetoencephalography. Alzheimers Dement (Amst). 2019 Dec; 11:450-462. PubMed ID: 31431918.
  • López-Sanz D, Bruña R, Delgado-Losada ML, López-Higes R, Marcos-Dolado A, Maestú F, Walter S. Electrophysiological brain signatures for the classification of subjective cognitive decline: towards an individual detection in the preclinical stages of dementia. Alzheimers Res Ther. 2019 06; 11(1):49. PubMed ID: 31151467.

2018

  • López-Sanz D, Suárez-Méndez I, Bernabé R, Pasquín N, Rodríguez-Mañas L, Maestú F, Walter S. Scoping Review of Neuroimaging Studies Investigating Frailty and Frailty Components. Front Med (Lausanne). 2018; 5:284. PubMed ID: 30349819.
  • López-Sanz D, Serrano N, Maestú F. The Role of Magnetoencephalography in the Early Stages of Alzheimer's Disease. Front Neurosci. 2018; 12:572. PubMed ID: 30158852.
  • de Frutos-Lucas J, López-Sanz D, Zuluaga P, Rodríguez-Rojo IC, Luna R, López ME, Delgado-Losada ML, Marcos A, Barabash A, López-Higes R, Maestú F, Fernández A. Physical activity effects on the individual alpha peak frequency of older adults with and without genetic risk factors for Alzheimer's Disease: A MEG study. Clin Neurophysiol. 2018 09; 129(9):1981-1989. PubMed ID: 30031969. PDF file PDF file.
  • Martínez JH, López ME, Ariza P, Chavez M, Pineda-Pardo JA, López-Sanz D, Gil P, Maestú F, Buldú JM. Functional brain networks reveal the existence of cognitive reserve and the interplay between network topology and dynamics. Sci Rep. 2018 Jul; 8(1):10525. PubMed ID: 30002460. PDF file PDF file.
  • López-Higes R, Martín-Aragoneses MT, Rubio-Valdehita S, Delgado-Losada ML, Montejo P, Montenegro M, Prados JM, de Frutos-Lucas J, López-Sanz D. Efficacy of Cognitive Training in Older Adults with and without Subjective Cognitive Decline Is Associated with Inhibition Efficiency and Working Memory Span, Not with Cognitive Reserve. Front Aging Neurosci. 2018; 10:23. PubMed ID: 29456502.

2017

  • Garcés P, López-Sanz D, Maestú F, Pereda E. Choice of Magnetometers and Gradiometers after Signal Space Separation. Sensors (Basel). 2017 Dec; 17(12):. PubMed ID: 29258189. PDF file PDF file.
  • López-Sanz D, Garcés P, Álvarez B, Delgado-Losada ML, López-Higes R, Maestú F. Network Disruption in the Preclinical Stages of Alzheimer's Disease: From Subjective Cognitive Decline to Mild Cognitive Impairment. Int J Neural Syst. 2017 Dec; 27(8):1750041. PubMed ID: 28958179. PDF file PDF file.
  • López-Higes R, Rodríguez-Rojo IC, Prados JM, Montejo P, Del-Río D, Delgado-Losada ML, Montenegro M, López-Sanz D, Barabash A. APOE ε4 Modulation of Training Outcomes in Several Cognitive Domains in a Sample of Cognitively Intact Older Adults. J Alzheimers Dis. 2017; 58(4):1201-1215. PubMed ID: 28550244. PDF file PDF file.
  • López-Sanz D, Bruña R, Garcés P, Martín-Buro MC, Walter S, Delgado ML, Montenegro M, López Higes R, Marcos A, Maestú F. Functional Connectivity Disruption in Subjective Cognitive Decline and Mild Cognitive Impairment: A Common Pattern of Alterations. Front Aging Neurosci. 2017; 9:109. PubMed ID: 28484387. PDF file PDF file.

2016

  • López-Sanz D, Bruña R, Garcés P, Camara C, Serrano N, Rodríguez-Rojo IC, Delgado ML, Montenegro M, López-Higes R, Yus M, Maestú F. Alpha band disruption in the AD-continuum starts in the Subjective Cognitive Decline stage: a MEG study. Sci Rep. 2016 11; 6:37685. PubMed ID: 27883082. PDF file PDF file.
  • López ME, Turrero A, Cuesta P, López-Sanz D, Bruña R, Marcos A, Gil P, Yus M, Barabash A, Cabranes JA, Maestú F, Fernández A. Searching for Primary Predictors of Conversion from Mild Cognitive Impairment to Alzheimer's Disease: A Multivariate Follow-Up Study. J Alzheimers Dis. 2016 03; 52(1):133-43. PubMed ID: 27060953. PDF file PDF file.

2014

  • Coullaut-Valera R, Arbaiza I, Bajo R, Arrúe R, López ME, Coullaut-Valera J, Correas A, López-Sanz D, Maestu F, Papo D. Drug polyconsumption is associated with increased synchronization of brain electrical-activity at rest and in a counting task. Int J Neural Syst. 2014 Feb; 24(1):1450005. PubMed ID: 24344693. PDF file PDF file.

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